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Why are you overweight? Too much fast food - or maybe it's genetics? (PDF)

Obese people — those with a BMI of 30 to 34.9 — have a 44 percent higher risk of death from any cause compared with those in the most-favorable range, according to a study in the New England Journal of Medicine.
A study by researchers at UCLA say genetics plays a bigger role in weight gain and obesity, perhaps as big as dietary choices.
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If you’re convinced your family genes are the reason why you seem to gain those extra pounds so easily, UCLA scientists say you might be right. 

In their first-of-a-kind study in the journal Cell Metabolism, researchers on the Westwood campus compared the metabolic responses of more than a hundred strains of mice fed a high-fat, high-sugar diet.  

They placed the mice on a normal diet for the first eight weeks of life, then switched them for the following eigth weeks to a high-fat, high-sugar diet that mimicked a fast-food diet.

During the “fast-food” style feeding, the fat of each mouse was measured at five points. When researchers compared the measurements, they discovered body-fat increases ranging from 0 percent to more than 600 percent among the mouse strains – suggesting that DNA plays a greater role in packing on the pounds than does overconsumption. 

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The study, funded in part by the National Institutes of Health, challenges the prevailing notion that fast-food consumption coupled with a sedentary lifestyle is the most significant factor contributing to the nation’s obesity epidemic.

The researchers say their findings emphasize the importance of genetics in controlling obesity.

Cell Metabolism UCLA Study

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