The Brief

A panel of vaccine advisers to the federal government — now embroiled in controversy under the leadership of Health Secretary Robert F. Kennedy Jr. — has voted in favor of changing the childhood vaccine schedule.
On Thursday afternoon, the Advisory Committee on Immunization Practices, or ACIP, voted 8-3 to change the current recommendations that allow children under 4 to receive the MMRV vaccine, a combination shot for measles, mumps, rubella and chickenpox (or varicella).
The vast majority of children in the U.S. — about 85% — get separate shots for MMR and chickenpox, though parents currently have the option to give their children the single shot to cover all four diseases.

More: California releases its own vaccine recommendations as RFK shifts federal policy

The panel's votes still require final approval from the acting CDC director Jim O'Neill, an ally of Secretary Kennedy's who's expected to greenlight their recommendations.

The panel, which advises the Centers for Disease Control and Prevention, also debated changes to the current recommendations for the hepatitis B vaccine. It will hold that vote Friday, and several members including the chair Martin Kulldorff made comments supportive of the idea.
Also on Friday, the panel will vote on recommendations on who should be eligible for the latest COVID-19 vaccines.

The MMRV vote will not affect the Vaccines for Children program — the committee decided to stick to the status quo for that program. That means it can still pay for these shots if parents opt to have them. But the Children's Health Insurance Program and Medicaid will be affected by the vote and may not cover these shots anymore.
The moves to overhaul the children's vaccine schedule represent the latest victory in Secretary Kennedy's long-running campaign to reshape policy. There was vocal opposition to the proposed changes from representatives of major medical groups who were present at the meeting.
"A question I've had all along through these discussions is why? Why are we addressing this hepatitis B vaccine recommendation? Is there really a reason?" asked Dr. Flor Muñoz, a pediatric infectious disease clinician who spoke at the meeting.
The proposed changes to the vaccine schedule also run counter to the hours of data presented by the CDC's own scientists throughout the meeting on the rationale for these recommendations.
Many in public health had warned that Kennedy was aiming to retool the vaccine schedule, after he replaced all 17 members of ACIP with his own handpicked roster, including five members he added this week. Many of those he chose have a history of being critical of vaccines.

MMRV no longer recommended for kids under 4

Tension between the committee and the medical establishment surfaced throughout the discussion over changes to the MMRV vaccine guidance.
At issue was evidence, presented by CDC staff, showing a slightly increased risk of fever-related seizures in children ages 12-23 months after receiving the MMRV shot compared to the MMR, which concerned some committee members.
"I would go with the option that seems to be safer," said ACIP member Retsef Levi, an MIT professor of operations management who gained prominence during the pandemic for criticizing COVID vaccines.
But Dr. Cody Meissner, a pediatrician at Dartmouth College and ACIP member, pointed out that fever-related seizures, while "frightening" for the family, are not uncommon. They occur in 3% to 5% of all children.
"Every pediatrician is experienced in febrile seizures. We know that the prognosis is excellent," he said.
Removing the MMRV shots from the vaccine schedule for children under age 4 would spark more public confusion, compromise insurance coverage and potentially lead to fewer kids being vaccinated, said Dr. Jason Goldman, president of the American College of Physicians who is acting as a liaison to the committee.
"I urge this committee not to change the recommendations if they truly want to give the power to the parents to decide what is best for their child," he said.
Several liaisons from major medical groups criticized the committee's process.
Goldman said it failed to bring in the voice of subject matter experts, clinicians and patients, noting that the representatives from medical groups had been removed from ACIP workgroups.

A potential break with existing policy on hepatitis B

The proposed changes to the hepatitis B vaccine schedule would mark a major departure — one that pediatricians and medical groups caution could reverse decades of progress in lowering rates of illness in the U.S.

Existing policy is to give the vaccine to all babies at birth regardless of the mother's hepatitis B status. The new recommendation would upend this, instead guiding doctors to screen all mothers and offer the vaccine only to those who do not test negative in an initial screening.
Several new ACIP members questioned why a universally given birth dose was necessary, if mothers could be adequately screened ahead of time.
"Are we asking our babies to solve an adult problem?" said Dr. Evelyn Griffin, an OB-GYN and ACIP member, "Are we trying to lower the prevalence of hepatitis B in a high-risk population by vaccinating them on day one?"
But CDC scientists explained that gaps in prenatal screening could leave many babies vulnerable to catching a debilitating, sometimes fatal illness. And an infant could be infected by exposure to someone else in the household who is infected — around half of people with hepatitis B don't know they have it.

"I have not seen any data that says that there is any benefit to the infant of waiting a month, but there are a number of potential harms to the infants of waiting," responded Dr. Adam Langer, a CDC scientist who was presenting on the data.
Meissner echoed these sentiments, pointing out that efforts to identify high risk groups had failed in the past, which is why the recommendations were made in the first place.
"It's an extremely safe vaccine," said Meissne. "If we change the recommendations, we will increase the risk of harm based on no evidence of benefits because there will be fewer children who get the full hepatitis B series.

"We will be creating new doubts in the mind of the public that are not justified."

Political tensions around the vaccine guidance process

The meeting comes on the heels of a contentious Senate hearing on Wednesday with the recently ousted CDC director Susan Monarez.
Monarez testified that she was fired after clashing with Kennedy over his demands that she preemptively agree to approve vaccine recommendations from ACIP, and fire career scientists.
"He said the childhood vaccine schedule would be changing starting in September and that I needed to be on board with it," she said.
Kulldorff, an epidemiologist, acknowledged the "controversy" at the outset, with pointed comments against his critics — among them a slate of former CDC directors who have said the new members, selected by Secretary Kennedy, are "unqualified" and "share his dangerous and unscientific views. "
Kulldorff rebuffed the idea that he or others on the panel were "anti-vaxxers" and challenged the former directors to an "open public debate."
"If they want to be trusted, they should all accept," he said.
Another sign of the increasingly polarized nature of vaccine policymaking was the notable absence at this week's meeting of a liaison from the American Academy of Pediatrics — the leading national group representing pediatricians in the U.S. that would usually collaborate with the panel.
The AAP had decided to boycott the meetings, arguing federal vaccine policymaking is no longer a "credible process." Kennedy has barred professional medical groups such as the AAP from serving in their traditional roles as expert liaisons to workgroups of the advisory committee.
ACIP member Meissner said the AAP was making a "grave mistake not to participate" and "moving itself to irrelevance."
Dr. Susan J. Kressly, president of the AAP issued a statement Thursday noting the group had published its own immunization schedule "to ensure providers and families have evidence-based guidance rooted in the best interests of children's health."
The group continues to recommend that the combination MMRV shot "should remain an option for families," Kressly said.
Copyright 2025 NPR

This story first appeared on The LA Local.

Just inches away from where workers warm up handmade tortillas at Guisados in Pasadena, Pablomanuel Maldonado puts the finishing touches on different drinks before calling out to his customers.

“Provecho,” Maldonado, owner of coffee pop-up the Caffeinated Cart, says to each customer before quickly redirecting his attention to the next, treating each one like he’s known them for years.

Local taco chain Guisados partnered with the Caffeinated Cart to bring its coffee to the people of Pasadena in a space where Maldonado can chat up his customers and serve his Latino-inspired signature coffees. 

Nearly all of his drinks have names in Spanish, a nod to his Mexican roots. By far his best seller is the “Cereal Killer,” a cinnamon brown sugar latte with a cereal garnish, where customers can choose between Cocoa Puffs or Cap’N Crunch Crunch Berries. 

Pablomanuel Maldonado, owner of the Caffeinated Cart, prepares a Cereal Killer at Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

Though he’s only been operating at this location for the past three weeks, small touches — like Virgen de Guadalupe candles, a new coffee blend from local roaster Picaresca and a shiny new drink menu on the wall — make his corner of the restaurant feel welcoming.

“For the first time, I don’t feel tired. I feel mentally at peace, and it’s like, ‘Damn, this is what I love doing,’ you know?” Maldonado told The LA Local. “I get excited to come here. I get excited to get out of bed.” 

Maldonado recently transitioned from working full-time at Bristol Farms during the week and doing coffee pop-ups on weekends to serving coffee full-time at Guisados.

The Caffeinated Cart began in 2020 when Maldonado started selling bottled lattes in his hometown of Compton before eventually popping up at local markets like Angel City Market and the Beach Flea. 

Only a couple of years after he started, Maldonado was selling out at the pop-ups.  Today, he has over 23,000 followers on Instagram.

Maldonado’s partnership with Guisados began in 2025 via an Instagram story when owner Armando De La Torre Jr. put out a call for coffee pop-ups at his Guisados location in Long Beach. 

A photo illustration of the Caffeinated Cart’s most popular drink the Cereal Killer, a cinnamon brown sugar latte with a cereal garnish, at Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

After connecting with De La Torre, Maldonado began popping up outside the Long Beach location for six months. But Maldonado said permitting issues with the city’s Health Department forced him to stop. 

Nearly a year after their initial collaboration, De La Torre invited Maldonado to Pasadena to show off the space he had in mind for him, but the Caffeinated Cart owner had mixed emotions. 

Maldonado was concerned about going to Pasadena and leaving behind the community and regular customers he had in Long Beach, but he was excited by the idea of finally having a physical space, even if it wasn’t completely his own.

Pablomanuel Maldonado, owner of the Caffeinated Cart, hugs his former boss who visited him at his new coffee residency at Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

“We’re in a world where… everybody gatekeeps and then everybody stops each other from growing, and coffee’s been so welcoming, man,” Maldonado said. “The community I’ve built around me has just been so welcoming, and a lot of people just truly do trust us.”

Leo Abularach, co-owner of Picaresca in Boyle Heights, has been a longtime supporter of the Caffeinated Cart. He told The LA Local that he loaned Maldonado over $3,000 worth of equipment to help him get started. Abularach even let him use his business delivery service, so Maldonado would no longer have to run to the store for things like extra milk.

“He has always been there for Picaresca. He is part of our family,” Abularach said of Maldonado. “He is one of the kindest people I’ve ever met, and I think his personality is one of the reasons why people love the Caffeinated Cart.”

Pablomanuel Maldonado, owner of the Caffeinated Cart, pours coffee beans into a grinder at Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

Customers Adriana Acevedo and Eilene Gonzalez saw the Caffeinated Cart on TikTok. When they realized it was around the corner from their workplace, they decided to give it a try.

“It’s amazing. It tastes really good. Like, no notes. Amazing,” Acevedo said after finally trying the coffee in real life on a recent Wednesday morning. 

“Yeah, for first timers, now I think we’re going to be returners,” Gonzalez added with a laugh. 

Pablomanuel Maldonado, right, talks with customers Adriana Acevedo, left, and Eilene Gonzalez, centert, at the Caffeinated Cart inside of Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

The two praised the welcoming service offered by Maldonado, and after Acevedo mentioned she loves caffeine, Maldonado even gave her an additional shot.

“I’m all about making it affordable. I don’t charge extra for alternative milks. You want extra shots? Bro, get extra shots. I’m not going to charge you extra,” Maldonado said. 

“We’re all for the people,” he said. “We want to make sure people can still come back and not have to feel like ‘Was the $7 coffee worth it?’”

Though it was only a Wednesday, customers kept trickling in, keeping him busy throughout his shift, and even Maldonado’s old boss from Bristol Farms, Dina Urquilla, came to support. 

Maldonado said he’s still saving to open up his own shop in the future, but for now, he says he looks forward to making coffee every day in his corner of Pasadena.

A view of some of the trinkets at the Caffeinated Cart inside of Guisados in Pasadena, Calif. on Mar. 4, 2026.

(

Isaac Ceja

/

The LA Local

)

Warm temperatures are on tap again today as we head into a toasty weekend with temps set to reach the triple digits in desert communities.

L.A. County beaches will see daytime highs from 67 to 72 degrees. It'll be between 69 and 76 degrees along the Orange County coast. More inland areas like downtown L.A., Hollywood and Anaheim will see temperatures from 75 to 81 degrees.

Meanwhile, the valleys will see varying temperatures. Areas closer to the coast will see highs from 78 to 83 degrees, and further inland, temps will stay in the upper 80s, up to 89 degrees.

Meanwhile in Coachella Valley, temperatures will rise to 101 to 106 degrees.

Looking ahead to the weekend, the valleys will reach the 90s for Mother's Day, up to 100 degrees in the Antelope Valley too. Come Sunday, an Extreme Heat Warning kicks in for the Coachella Valley, where temperatures will stay in the low 100s, with up to 109 degrees possible. Make sure to stay hydrated!

Jessica Wang has experienced delay after delay for nearly two years as she tried to open Gu Grocery in Chinatown. Her father, a contractor, had told her it would take nine months.

Instead, she says, there have been issues with city permits, inspectors, inaccurate information, illness and wayward appliance installers which have pushed things back.

The community didn't take nearly as long. In two weeks, 134 donors contributed nearly $12,000 to keep Wang afloat. But money can't solve her problem — she still needs the city's approval to open the doors.

Wang signed the lease at the end of 2023, envisioning a Chinese-Taiwanese grocery store and community hub where seniors could use EBT to buy fresh tofu, where kids from nearby elementary schools could stop by after class, and where her mother, Peggy, could teach neighbors how to make their grandmother's pickles.

Now, more than two years into a five-year lease, and nearly out of money after paying for permits, buildout, and rent on a space she can't operate, Wang launched a GoFundMe campaign a few weeks ago. The response showed the community believes in Gu Grocery and wants to see it succeed. But she's still waiting for at least seven final inspections by the city before she can open.

The story of Gu

The name "Gu" carries layered meaning: the character 菇 means "mushroom" in Chinese, a traditional symbol of prosperity, while the sound "gu" also means "auntie" in Mandarin — honoring intergenerational caretakers. Wang's mission for the space is to provide a place to purchase Chinese-Taiwanese pantry staples and prepared foods, and to host community workshops.

The communal aspect is central to Wang's vision of social entrepreneurship, not solely focused on profit. In addition to workshops, Gu Grocery plans to accept EBT and offer senior discounts for those on fixed incomes.

"I wanted a space where I could share knowledge and share culture and also just learn from the community," Wang said.

Ultimately, she hopes to convert the store into a worker-owned co-op.

Wang grew up in the San Gabriel Valley and worked as a pastry chef at San Francisco's State Bird Provisions before a pre-diabetic diagnosis at age 29 prompted her return to L.A. She began volunteering with API Forward Movement, a local nonprofit focused on health equity and food access in AAPI communities, and saw firsthand the need during COVID food distributions at L.A. State Historic Park.

Chinatown had lost its last two full-service grocery stores in 2019. Last fall, the neighborhood lost another: Yue Wa Market, a small produce shop that had served residents for 18 years before rising rent and pandemic losses forced it to shut its doors. The closures hit especially hard in a neighborhood where, according to American Community Survey data, half of the residents are low-income and one in five are seniors 65 and older — many of whom rely on walking to shop.

Jessica Wang (center, in black) and her mother Peggy (left, in white and red) smile while serving customers at a farmer's market pop-up for Gu Grocery.

(

Daniel Nguyen

/

Courtesy Gu Grocery

)

Permitting woes

Much of bringing Gu Grocery to reality has been made possible by support from Wang's friends and family. Her father, Willie Wang, serves as her general contractor. When plans were submitted to the city in March 2024, he told her the buildout would take nine months if everything went smoothly.

Instead, she’s experienced delays from all directions, from slow bureaucracy, to issues with contractors. A hood installation contractor rescheduled multiple times, she said, then doubled his price the day before a rescheduled appointment. Drywall contractors said their workers had been detained by ICE and never returned.

The process hasn't just taken time — it's been expensive. One inspector approved a makeup air unit for the kitchen hood system, she said, only to have a senior inspector overturn the decision and order a complete replacement at nearly $6,000. Her father paid out of pocket — even as he was recovering from March surgery to remove a cancerous lung growth.

"Who would have thought that something an inspector asked us to do would be completely overturned by another inspector?" Wang said. "That's just so wild."

LAist has reached out to the city's Department of Building Services for comment but has not heard back.

The financial toll

Wang estimates she's spent more than $200,000 so far — more than $100,000 on buildout and permits alone, plus a full year of rent on a space she can't operate, equipment, insurance and taxes.

She draws no income from Gu Grocery. To cover personal expenses, she teaches fermentation workshops through her other business, Picklepickle, though that work has been inconsistent lately. Her health insurance doubled this year. The GoFundMe money, she said, is a "rainy day fund" in case she needs it to pay future bills.

The financial strain has touched her entire family. Her mother, who received a small inheritance when Wang's grandparents died, got scammed late last year trying to grow that money to help with the store. Targeted through online ads, she was convinced by an "investment tutor" based in Taiwan to hand over cash to a stranger in a parking lot.

"I didn't realize this would become part of what it's like to have aging parents in the age of technology," Wang said. "But it's scary how they get targeted."

Black sesame noodles from Gu Grocery's popup menu. Wang uses black sesame for higher nutritional value and plans to offer the dish as one of the prepared foods when the store opens.

(

Aunty J

/

Courtesy Gu Grocery

)

Rice balls with house pickles from a Gu Grocery pop-up. Wang has been teaching fermentation and pickling workshops for 15 years and plans to serve pickles alongside all meals when the store opens.

(

Aunty J.

/

Courtesy Gu Grocery

)

Addressing Chinatown's needs

Once Gu Grocery opens, it won't operate as a full-service market — there won't be a meat counter. Instead, it will function like a corner store with a focus on healthy prepared foods: butter mochi, sesame noodles and daily congee.

"Something that Chinatown has never had was prepared food that is EBT eligible," Wang said.

In 2020, Wang surveyed seniors through API Forward Movement's Tai Chi fitness program to understand their shopping habits following the closure of local grocery stores. Many told her they now ride the bus to Super King on San Fernando Road in Glendale, nearly 5 miles away, for produce deals, or rely on family members to drive them to 99 Ranch in Alhambra. Some grow their own food in gardening plots, Wang said, "but they can't produce everything they need."

Willie Wang (left), Jessica Wang (center), and Peggy Wang (right) pose inside Gu Grocery. The signs display the store's values in both English and Chinese — Willie's reads "body health" and Peggy's reads "mushroom auntie," playing on the dual meaning of "gu."

(

Daniel Nguyen

/

Courtesy Gu Grocery

)

The community response

When she launched her Go FundMe in mid-April, she was overwhelmed by the response. "I have a hard time asking for help," said Wang. "So actually receiving help, it's very moving."

The donors range from former pop-up customers and friends to a range of assorted well-wishers — a musician who had her food once at an event, fellow food business owners, farmer's market regulars and even her insurance agent.

"The generosity is beyond my expectations," Wang said. "Some of these people only had my food once. People are showing their support truly in a personal way and really believing in the vision."

The GoFundMe money helps Wang stay "afloat for now," but she's had to rethink her opening strategy. She won't be able to afford full inventory when she opens. Instead, she plans a phased opening: prepared foods only, served through a takeout window, then using revenue to slowly stock shelves with the retail items she originally envisioned.

The community raised more than $14,000 in three weeks. After nearly two years of delays, Wang is still waiting for permits. She hopes to open by Father's Day — her general contractor dad's birthday. But she's learned to expect the unexpected.

Many donors sent her direct messages saying simply: "We got this, Jess, we got you."