The Brief

The Food and Drug Administration intends to get tougher on vaccine approvals, as top officials raised concerns about the risk of COVID vaccines for children.

Speaking on Fox News Saturday morning, FDA Commissioner Marty Makary said the agency would no longer "rubber-stamp new products that don't work," claiming it made a "mockery of science."

Makary's comments came the day after FDA's top vaccine regulator, Dr. Vinay Prasad, told his team the agency would change its annual flu vaccine framework, update vaccine labels to be "honest," and make other changes to how it reviews vaccines, according to contents of an internal email reviewed by NPR and reported on first by a PBS News Hour correspondent and later by The Washington Post.

Prasad wrote that the FDA would also no longer authorize vaccines for pregnant women without stricter requirements. And for pneumonia vaccines, manufacturers will have to prove they reduce disease rather than show they generate antibodies. He also raised questions about giving multiple vaccines at the same time, which is standard practice.

The changes could make it much more difficult and expensive for vaccines to get approved, further limiting the availability of vaccines, which are considered among the safest and most effective tools for protecting people against infectious diseases.

While all vaccines carry some risks, most public health experts argue the current process for vetting vaccines before marketing has long assured that the benefits of vaccines outweigh their risks. Studies required after vaccines are approved and surveillance systems, including the Vaccine Adverse Event Reporting System (VAERS), also flag potential safety issues once vaccines are in use.

FDA says an analysis links COVID shots to some deaths

Makary said on Fox News that 10 children had died from the COVID shot during the Biden administration, but did not offer specifics about how the FDA came to that conclusion. Millions of children have received the vaccine. 

Officials with the Department of Health and Human Services and Food and Drug Administration didn't immediately respond to requests for comment on the COVID analysis and changes to vaccine review standards.

According to the FDA email from Prasad, he told the agency's biostatistics and pharmacovigilance team to analyze 96 reported deaths from 2021 to 2024, and they determined 10 children died "after and because of" the COVID vaccine. But Prasad said the true number was likely higher.

Dr. Paul Offit, who directs the Vaccine Education Center at the Children's Hospital of Philadelphia, said in a text message that Prasad has not shared the evidence that these vaccines killed 10 children.

"Because he doesn't provide any evidence, he is asking us to trust him on an important issue," Office said. "All this will do is scare people unnecessarily. At the very least, he should provide all the evidence he has so that experts in the field can review it and decide whether he has enough data to prove his point."

Dr. Jesse Goodman, a professor at Georgetown University who held Prasad's job at FDA from 2003 until 2009, said in an email that the FDA's Center for Biologics Evaluation and Research, which oversees vaccine approval, has been "recognized globally as a gold standard regulator." Goodman defended "immunologic endpoints like antibody levels" for the accelerated approval of pneumonia and influenza vaccines. He said science supports their use and they are confirmed with studies after approval: "These approaches have helped provide children and adults with timely access to safe and effective vaccines, saving many lives."

Michael Osterholm, an epidemiologist at the University of Minnesota, reviewed the email from Prasad and challenged his statement that "COVID-19 was never highly lethal for children." Osterholm also questioned the FDA's latest analysis of adverse event reports attributing the 10 deaths to COVID vaccines.

"Prasad's email is filled with factual mistakes and misrepresents both the severity of COVID in children (1597 deaths in 2020-2022) and how the US responded to the first signals of possible vaccine-associated pediatric deaths in May 2021," Osterholm wrote in an email to NPR.

"While Prasad's email notes 10 such deaths, these cases have never been presented for review by the medical and public health communities or published in the medical literature," Osterholm continued. "Given the record of this Administration to misrepresent scientific data regarding vaccines, until these cases have been reviewed by an expert third party, like the National Academy of Science[s], we can not accept the fact they are vaccine-associated deaths."

Surveillance system collects vaccines reports

The FDA makes public data from the VAERS surveillance system co-sponsored by the Centers for Disease Control and Prevention. But the FDA cautions, "it is important to note that for any reported event, no cause and effect relationship has been established." In his email, Prasad wrote that "with case reports, causality is typically assessed on a subjective scale. In this scale ranging from certain to unlikely — certain, possible/likely, and probable are broadly considered as related to the product."

Makary said on Fox News that when the COVID shot was first rolled out, it was "amazing" for people at high risk of coming down with severe disease, but things have changed.

"Back in 2020, we saw a reduction in the severity of illness and lives saved, but now recommending that a 6-year-old girl get another 70 million COVID shots — one each year for the rest of her life — is not based on science. And so we're not going to just rubber stamp approvals without seeing some scientific evidence."

The claim is the latest move by Trump administration health officials questioning the safety and effectiveness of vaccines and how the government has regulated them. Health Secretary Robert F. Kennedy Jr. has long questioned vaccines.

The FDA restricted eligibility for the updated COVID vaccines in August after announcing the agency planned to require more evidence about the shots' safety and effectiveness going forward.

CDC committee will meet to review vaccine policies

The FDA email on vaccine policy comes just before the CDC convenes a crucial two-day meeting of that agency's influential Advisory Committee on Immunization Practices on Dec. 4-5. The committee is in the process of conducting a major review of how children are inoculated against dangerous infectious diseases such as measles, mumps, rubella, polio and hepatitis B.

Many public health experts are concerned the committee will upend the childhood vaccination schedule. It could move to delay the timing of some inoculations, space out vaccinations and call for the reformulation of some vaccines. Taken together, the moves could result in fewer children getting protected and the resurgence of once-vanquished diseases.

Asked about Makary and Prasad's claims that the COVID vaccine caused deaths among 10 children, Moderna, whose COVID vaccine is approved for children as young as 6 months old, pointed to a statement it made in September. The company says that multiple published, peer-reviewed studies from a variety of sources show its shot is safe and that it is "not aware of any deaths in the last year or pertinent new information from prior years."

Moderna says it monitors its vaccine's safety along with regulators in more than 90 countries. "With more than one billion doses distributed globally, these systems — including in national health systems across Europe, the United Kingdom, Canada, Australia and the U.S. — have not reported any new or undisclosed safety concerns in children or in pregnant women."

Pfizer did not immediately respond to requests for comment.
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A year after former Orange County Supervisor Andrew Do reported to federal prison to serve time for bribery, evidence continues to surface of widespread corruption and mismanagement of taxpayer dollars during his time in office.

A county report released Wednesday found that millions of dollars in COVID-era contracts and grants were directed by Do and another top county official with no competitive bidding and little to no accounting of how the money was spent. Overall, the report paints a picture of a local government facing an unprecedented public health crisis, flush with federal relief dollars, but with minimal guardrails to ensure those dollars were properly spent.

For example, Do awarded a $500,000 small business grant in May 2021 to Bridgecreek Realty Investment Corp. to expand outdoor dining in Little Saigon during the pandemic. But the audit noted that the contract never required Bridgecreek to provide supporting documentation for how the money was spent — such as invoices or receipts. In the end, there is no documentation for how more than half of the taxpayer funds were used.

LAist left a voicemail with Frank Jao, owner of Bridgecreek, requesting comment and will update this story if we receive a response.

The audit also details the numerous times that top county officials were alerted to, but didn’t act on, potential irregularities regarding millions in county funds awarded to a nonprofit connected to Do’s adult daughter, Rhiannon Do. The audit details one occasion in which Clayton Chau, the former county health care director, reprimanded a subordinate for raising concerns and stated “that Supervisor Do was a lawyer and he would know if there was a conflict.”

Chau did not return a text and message from LAist left on his voicemail. We will update this story if we receive a response.

Frank Kim, the former Orange County chief executive, was also interviewed by the auditors. The audit said he was also aware of the alleged conflict of interest, but failed to consult with the county’s top lawyer at the time. Instead, according to the audit, he relied on the word of Do’s then-chief of staff, Chris Wangsaporn, who assured Kim there was no conflict.

LAist left a voicemail on Wangsaporn’s cellphone seeking comment and will update this story if and when we receive a response.

“It’s not an excuse, but that was a strange time,” Kim, the former county CEO, told LAist on Wednesday. Referring to the pandemic and the audit’s findings, Kim added: “None of the processes were really set up to deal with emergencies.”

Kim told LAist he had trusted the supervisors and top county staffers.

“I never thought there would be fraud," he said. “These were people I had worked with for a long time. I never thought they would do something like that.”

Several county supervisors were quick to react to the audit findings, calling for even deeper investigation into what Supervisor Donald Wagner called “potential additional abuses of taxpayers’ dollars.”

Supervisor Janet Nguyen, who was elected to replace Do, said Do and Chau had “scammed taxpayers in the most difficult time of their lives.” She also said the audit showed the county had “routinely bypassed its own rules” for contracting with outside entities.

Supervisor Katrina Foley said the report exposed “deficiencies in oversight and accountability that the board continues to address,” adding that the county must complete the next two scheduled phases of the forensic audit to “uncover remaining problems, strengthen our controls, and protect taxpayers from corruption and abuse.”

The backstory

The new report is the result of the second phase of a forensic audit of major pandemic-era contracts ordered by the O.C. Board of Supervisors in the wake of the Do scandal. The outside firm Weaver is conducting the audit.

Do pleaded guilty to a federal bribery charge in 2024 following a more than year-long investigation by LAist that found he directed some $13 million in taxpayer funds to an organization affiliated with his daughter, Rhiannon, who was a student at the time. Most of that money was slated to provide meals and services for needy residents of Do’s district during the COVID-19 pandemic.

Instead, at least $550,000 of the funds was rerouted back to Do and his two daughters in the form of bribes, according to federal officials, while just 15% was used to feed residents.

Do will complete his first year in prison on Saturday. He’s scheduled for release in June 2029, according to the federal Bureau of Prisons.

How to watchdog your local government

One of the best things you can do to hold officials accountable is pay attention. Your city council, board of supervisors, school board and more all hold public meetings that anybody can attend. These are times you can talk to your elected officials directly and hear about the policies they’re voting on that affect your community.

• Read tips on how to get involved.
• The Orange County Board of Supervisors meets on alternating Tuesdays at 9:30 a.m. at 400 W. Civic Center Drive, Santa Ana. You can check out the O.C. Board of Supervisors full calendar here.
• Learn how to submit a public comment to the O.C. Board of Supervisors.

A Los Angeles County grand jury has indicted Nick Reiner on murder charges in the killings of his parents, Rob Reiner and Michele Singer Reiner, and adds the allegation that he was lying in wait before attacking them.

The grand jury, which had been meeting in secret, returned the indictment on July 20, and it was unsealed Wednesday, when 32-year-old Nick Reiner entered a not guilty plea.

Rob Reiner, a director, actor and Hollywood luminary, and his wife, a photographer and producer, were stabbed to death in their home in the upscale Brentwood section of Los Angeles on Dec. 14. Nick Reiner was arrested within hours and charged two days later.

Why the indictment matters

The grand jury indictment is a major step toward trial and allows prosecutors to skip California’s preliminary hearing process, where evidence is publicly aired.

Lying in wait means a suspect waited for or hid from victims in order to ambush them, and as an allegation it’s meant to show premeditation. A finding that he was lying in wait along with a murder conviction would make Reiner eligible for the death penalty, but prosecutors said they haven’t decided whether to seek it.

“This was a profound betrayal by someone who was loved and trusted by the very people he is accused of killing,” Los Angeles County District Attorney Nathan Hochman said in a statement. “We hope that by having a grand jury return an indictment in this case it will bring us one step closer to a trial and achieving justice.”

What does the indictment say?

Prosecutors have said nothing about possible motives, and leaks in the case have been virtually nonexistent on both sides.

The Los Angeles County chief medical examiner told The Associated Press he would like to make their autopsy reports public, but a court order has prevented him from doing so.

The unsealed indictment reveals few new details in a case that has been shrouded in secrecy. It does not explain how or why Reiner was lying in wait. Without elaborating, prosecutors have said since December that the parents were stabbed. The indictment includes a special allegation of use of a deadly weapon — a knife — that could also contribute to a stiffer sentence.

What about the trust funds?

The indictment comes as Reiner is seeking unpaid money from a trust his parents established for him, saying he needs it to help in his defense.

Reiner said in a court petition that the trustees who oversee the funds have denied them to him without legal justification. The money was to have gone to Nick Reiner even if his parents were alive, legal filings say. The petition says the trust has at least $1.5 million in assets, but trustees would not share the exact amount.

“Nick loved his parents, and he is devastated by their deaths. But the facts about what did and did not happen to them are not at issue,” the petition says.

He is seeking to hire back high-profile criminal defense attorney Alan Jackson, who initially represented him before Reiner’s siblings would no longer agree to fund his defense and a public defender took over.

A hearing on the petition is set for next week.

The LA County Public Defender’s Office, which is representing Reiner, declined to comment on the indictment.

Why is this process shrouded in secrecy?

California prosecutors can charge a defendant and take the case through a preliminary hearing — a sort of trial in miniature where evidence is publicly aired and a judge decides whether it should be sent to trial — as recently happened with singer D4vd.

Or they can use a grand jury to go through the process in secret. They can also publicly file charges and later seek a secret grand jury indictment, essentially creating a new version of the case, as happened here and in the Los Angeles prosecution of Harvey Weinstein.

Remembering Rob Reiner

Rob Reiner began as an actor, starring in the TV sitcom, “All in the Family,” as Michael “Meathead” Stivic, the liberal son-in-law to a much more conservative and bigoted Archie Bunker, played by Carroll O’Connor. Reiner won two Emmy Awards for the role, and last month got a posthumous Emmy nomination for his work as a guest star on “The Bear.”

He became a prolific director whose work included some of the most memorable and endlessly watchable movies of the 1980s and ’90s. His credits included “This is Spinal Tap,” “Stand By Me,” “A Few Good Men,” and “When Harry Met Sally…” during the production of which he met photographer Michele Singer. They wed soon after and were married for 36 years.

Nick Reiner was the second of the three children they had together. He and his father co-wrote the script for the 2015 film “Being Charlie,” which was partly based on the son’s teenage struggles with addiction and homelessness.

His older brother Jake Reiner wrote in April that the experience of losing his parents and having his brother at the center of it was “a living nightmare” that is “too devastating to comprehend.”

The City of L.A. is still on the hook for a potentially infinite amount of money if the 2028 Olympics and Paralympics are a financial failure.

But in the latest attempt to moderate that risk, the Los Angeles City Council voted 10-4 Wednesday to approve an overdue agreement with the private Olympic organizing committee LA28.

What to know about the agreement 

Matt Szabo, the City Administrative Officer who negotiated the agreement with LA28, spoke at Wednesday's council meeting.

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The deal lays out how LA28 will repay the city for services rendered during the Games, like traffic control. It establishes that the city will seek reimbursement for the cost of policing venues from the federal government, which is overseeing Olympics security.

The council also approved an amendment to a 2021 agreement between the city and LA28 that allows the city to tap an LA28 contingency fund to recoup security costs if the federal government doesn't cover those expenses.

Matt Szabo, the City Administrative Officer who negotiated the agreement with LA28 alongside the city's Chief Legislative Analyst Sharon Tso, acknowledged the agreement had big limitations. At the same time, he told the council Wednesday that he believed it was the best bet at protecting the city.

" This is not an agreement that is intended or even has the capability of eliminating risk that the city has agreed to take on," Szabo told the council. "The purpose is to limit the risk to the greatest extent possible. And we do believe that it achieves that."

Still, some in city government said the agreement doesn't go far enough to protect taxpayers.

"Despite being delivered months behind schedule, it still fails to establish a clear baseline of City services, financial protections for Los Angeles taxpayers, and accountability that the City needs to successfully host the Games," said Councilmember Monica Rodriguez, who was one of four councilmembers to vote against the agreement, in a statement.

The agreement now heads to Mayor Karen Bass and Council President Marqueece Harris-Dawson for a signature with LA28.

Concerns about the deal with security costs looming

A sticking point for dissenters is security costs — which are expected to be massive. Organizers and the city are counting on the federal government to pay for public safety at Olympic venues that are considered part of a "national special security event."

LA28 has not included security costs in its $7.1 billion budget — a fact that City Attorney Hydee Feldstein Soto criticized earlier this year.

The federal government has so far allocated $1 billion for security costs for the Olympics. Exactly where those federal funds will go has not yet been determined, and there's no guarantee they will cover all of L.A.'s policing costs.

Los Angeles Police Chief Jim McDonnell estimated LAPD personnel costs alone could exceed that total, putting the cost for his department at $1.15 billion in one budget memo issued earlier this year.

Protections for the city are limited

Under an agreement approved by the council Wednesday, if L.A. is not reimbursed by the federal government for all its eligible expenses, it could dip into LA28's contingency fund of $270 million before the private organizing committee could use that money for any legacy projects.

Here's the catch: that bucket will first be used for any costs that Olympics organizers still owe if they run out of revenue — meaning if the Olympics don't turn a profit, the city's access to that money will depend on how much is left for the taking.

" LA28 has no real incentive not to bankrupt us," said Chris Tyler with the community organization Strategic Actions for a Just Economy in public comment. "And if they come in under-fundraised and over-budget, taxpayers will be on the hook for billions of dollars potentially."

Szabo, the city administrative officer, said later in the council meeting that the Olympics turning a profit was in L.A. and LA28's best interest.

" We are joined at the hip here," he said. "They want a successful Olympics. They want to have a successful legacy for those '28 Olympics. We want a successful Olympics."

The agreement is late — and some still say it was rushed

At the Wednesday meeting, several city council members introduced six amendments to the agreement with LA28, aimed at clarifying or tightening LA28's obligation to the city.

All but one proposal was referred to committee for further discussion, and weren't included in the final agreement. Council President Harris-Dawson warned the council that approving amendments would send the city back into negotiations with LA28 that had already dragged on for years.

Councilmember Eunisses Hernandez, who introduced two amendments seeking to regularly audit LA28's finances and guarantee reimbursements for unexpected "health and safety incidents" related to the Games, responded saying she hadn't had adequate time to consider the deal.

" I have Dodger Stadium in my district, which is an Olympic venue," she said. "So you're asking me to make a decision on something that's going to impact us for years to come, and particularly within the heart of my district, but I was only briefed two weeks ago."

City Controller Kenneth Mejia also criticized the process in an interview with LAist.

" Why are we rushing through this thing so fast?" he said, calling the deal "fiscally irresponsible" and asking: "Why are we not trying to maximize protections for the city today?"

Some, though, told the council they thought the agreement, which was due Oct. 1, 2025, was already too delayed.

" Every additional month of delay reduces the run[way] for detailed planning for our businesses," said Jacqueline Iniguez with the L.A. Area Chamber of Commerce in public comment. "The city and LA28 now need to move forward together quickly to keep the 2028 games on track." 

More big agreements ahead 

Jacie Prieto Lopez, a spokesperson for LA28, said Olympics organizers were proud of the final agreement, saying it "delivers on our commitment to execute a safe, secure, and fiscally responsible Games that benefit Los Angeles for decades to come."

The agreement approved by council Wednesday will serve as a master document as the city now goes on to execute "Venue Service Agreements" – even more specific agreements between LA28 and the city on what services will be provided at each venue in the city.

Other municipalities hosting Olympic venues will also have to execute their own agreements with LA28 on reimbursement.

How those agreements are inked will also have implications for the city of Los Angeles. It's the financial backer of the entire Olympics, whether the venues fall inside city boundaries or not.

On Wednesday morning, Los Angeles Unified School District students returned to campuses for the first day of school. For many, that meant coming back to schools located near a Boyle Heights warehouse that burned for more than a week in June.

The disaster forced the district to relocate summer programs at several nearby schools, including Christopher Dena Elementary. But on the morning of back-to-school, Maria Bravo said she was ready for her third-grade son and sixth-grade daughter to get back into Dena Elementary classrooms

“ I know that they're going to be in a good place here,” Bravo said. She said her kids needed a new routine after a summer spent largely indoors, trying to avoid the heat and the smell of rotting food wafting from the Lineage warehouse.

“They're going to find ways to keep them busy and active, and at the same time safe," Bravo said.

Principal Robert Salazar said classrooms have air purifiers and there’s a plan to bring students inside if rotting food smells interrupt recess or lunch.

“ It's like three plans — we have, A, B and C,” he said.

Karoline Linde, a 5th grade teacher at Dena Elementary, brought souvenirs back from a summer trip to Croatia to include in her Medieval Times unit. " You want the kids to succeed. You want the kids to do their best," Linde said. "That's my job as an educator. How am I gonna do that?"

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However, as has been true throughout the summer, the odor varied across the neighborhood.

At Eastman Elementary, Ivett Dominguez walked her child to Eastman Avenue Elementary School and told LAist the smell outside was “consistent and annoying,” but that she didn’t notice it inside her son’s classroom.

Other parents were more critical of the district’s decision to reopen the schools while the clean-up continued.

LAUSD Superintendent Andrés Chait visits a classroom at Belvedere Middle School the first day of the 2026-2027 school year.

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Andrés Chait, LAUSD’s superintendent, said preliminary attendance results showed about 92% of students enrolled at campuses near the burned warehouse came to the first day of school, exceeding the district’s overall attendance rate of 90%.

“[I have]  gratitude to our communities for having faith in us and in the measures that we took,” Chait said.

He said the district will take “corrective action” where lead and other toxins are found and that he’s directed his team to look into other ways for the district to advocate for climate justice.

“ Our primary role always is to provide education and academic advancement, but I think we can do more than that,” Chait said.

Some environmental health experts and advocates who reviewed the district’s testing results told LAist that school officials have more work to do on testing and cleaning at some campuses.

Environmental testing raises questions about long-term fire impact

District officials said environmental tests — which they released the day before school started — concluded the Boyle Heights warehouse fire did not result in widespread contamination at nearby campuses and affirmed the decision to reopen schools.

Soil tests found lead levels that exceeded California’s acceptable threshold at two elementary school campuses — Christopher Dena and City Terrace. The district said in its report that staff will evaluate whether more testing or cleanup at those sites is needed.

Carlos Torres, director of LAUSD’s Office of Environmental Health and Safety, said the front lawn at City Terrace and the tree wells at Dena, where elevated levels of lead were detected, have been fenced off.

At Christopher Dena Elementary in Boyle Heights, school officials fenced off a tree and a patch of soil where environmental testing found elevated levels of lead.

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Torres said the district doesn’t believe the lead is tied to the warehouse fire.

“Most likely this could be from things like lead-based paints from use in the past. It could be from agricultural use,” Torres told LAist on Tuesday. “There isn't such a thing as clean soil anywhere.”

The district said the levels of several other substances, including ammonia, formaldehyde and manganese, were low enough that they did not threaten the health of students or school staff.

Teacher Jose Salazar introduces Belvedere Middle School students to the different components of the career and technical education class which include engineering, child development and criminal justice on the first day of the 2026-2027 school year.

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Jill Johnston, an associate professor of environmental and occupational health at UC Irvine, agreed that elevated lead levels in the soil at nearby schools could have been present before the warehouse fire.

But she expressed concern about test results for ammonia at three schools within two miles of the Lineage warehouse: Eastman Avenue Early Education Center, Humphreys Avenue Elementary School and Stevenson College and Career Prep.

Two indoor samples and one outdoor sample from those campuses were found to have between 319 and 327 micrograms of ammonia per cubic meter.

“Ammonia is a respiratory irritant,” Johnston said. “It can affect lung function, particularly in kids… Breathing in ammonia, particularly at levels that are much higher than background concentrations, is something we want to try to avoid, especially for vulnerable kids.”

California’s Office of Environmental Health Hazard Assessment sets a 200 microgram safety limit for chronic exposure to ammonia, meaning situations where people are breathing in the chemical compound continuously. District officials noted that the test results were far below the state’s 3,200 microgram limit for acute exposure, meaning about an hour or less.

Johnston said closing schools would have been a difficult decision for district officials. But she said additional scrutiny and monitoring at those three schools is warranted.

“If they're also kids from the neighborhood, they're being exposed at home,” she said. “It just builds this evidence that we've been observing over the last several weeks, that toxic chemicals associated with the activities at Lineage are getting into the community, and in this case, is getting inside the schools.”

East L.A. has a long history of pollution linked to nearby freeways and dense industrial development. In May, about 25,000 gallons of crude oil spilled into the streets after an underground pipe ruptured.

“This continues to remind us where our schools are located and how vulnerable our communities and schools are,” said Rocío Rivas, school Board vice president and representative for the neighborhood. “I think it's important to elevate the testing and continue to monitor regardless if there's a fire or not.”

The teachers union sent a letter to the superintendent on Aug. 6 with more than a dozen demands related to Boyle Heights schools, including additional environmental testing, heating, ventilation and cooling system upgrades.

“Fire-impacted school communities deserve more than assurances — they deserve an actionable plan that puts health and safety first,” wrote Gloria Martinez, president of United Teachers Los Angeles.

LAist reporter David Wagner contributed to this story.