Since 2000, opioid pain medications have been involved in the deaths of more than 165,000 Americans.
There are no easy answers when it comes to dealing with this crisis, but some drug companies believe that new versions of these drugs could play a big part.
Now they're trying to spread that message to regulators and lawmakers.
Associated Press reporter Geoff Mulvihill and Liz Essley Whyte of the Center for Public Integrity have spent most of this year poring over hundreds of documents and lobbying data spanning the last decade. They spoke to Alex Cohen for more.