Health officials warn about flea-borne typhus outbreak in Pico Union

This story first appeared on The LA Local.

A local outbreak of flea-borne typhus is spreading in the Pico Union neighborhood, according to health officials. Five cases have emerged in the city of Los Angeles with all five patients being hospitalized and recovering. 

The outbreak is being investigated by the Los Angeles County Department of Public Health who are hoping to minimize the spread of the infection.

Infections occur when feces from infected fleas are rubbed into cuts or scrapes on the skin or rubbed into the eyes. 

Symptoms include fever, body aches, headaches, nausea and rashes. They can appear within one to two weeks after becoming infected. There is no vaccine for flea-borne typhus but it can be effectively treated with antibiotics when diagnosed early.

According to the DPH the best way to prevent illness is to reduce exposure to fleas and animals that may carry them. This includes stray animals, rodents, and other wildlife such as opossums. 

“Community members can help protect themselves and their neighbors by keeping pets on flea control year-round, avoiding stray animals, and making sure wildlife cannot live in or around their homes,” Los Angeles County Health Officer Muntu Davis said in a statement.

Flea-borne typhus has increased in Los Angeles since 2010, with an all time high of 220 cases in 2025. The highest ever number reported in L.A. County.

The DPH advises residents to protect themselves and their pets by routinely using flea control products, keeping pets indoors as much as possible, and using EPA-registered insect repellent labeled for protection against fleas when outside.

They advise keeping pet food indoors to not attract wild or stray animals, as well as not feeding or touching any free-roaming animals.

Keeping yards free of debris and free of overgrown plants or bushes can also help wild animals avoid the area. It is recommended to keep trash in tightly closed containers, and to close off crawl spaces and openings where animals can enter, hide, or find food.

Infected animals do not typically show signs of illness and flea-borne typhus does not spread from person to person. Animal owners can be infected by touching their infected pets or if infected fleas are on the animal.

In 2025, nearly 90% of people diagnosed with flea-borne typhus required hospitalization, according to the DPH. All age groups are susceptible to catching typhus with documented cases in people ranging in residents from 1 – 85 years old, according to officials.

The county advises residents to get checked sooner rather than later, and to continuously be on the lookout for wild animals. The city will look to deal with an increase in cases since 2024.  

Residents can learn more about flea-borne typhus and prevention: ph.lacounty.gov/Typhus