Search Warrant Affidavit: 'Lethal Levels' of Drug Killed Michael Jackson

Michael Jackson Inves_chun.jpg
Drug Enforcement Agency investigators are seen through a window during a raid at the Mickey Fine Pharmacy in Beverly Hills last Friday. Federal drug agents raided this pharmacy Friday as part of the ongoing investigation into Michael Jackson's death. (AP Photo/Damian Dovarganes)

The July search warrant affidavit that officials used to raid the Houston offices of Michael Jackson's personal doctor was unsealed today, offering up what has been speculated for weeks: "lethal levels" of anesthetic propofol killed the pop star.

Conrad Murray told poice he had been treating Jackson for insomnia for about six weeks, according to the LA Times. He would give 50 milligrams of propofol every night, but fearing that Jackson was getting addicted to it, Murray began to wean him off of it by lowering the doses.

According to the affidavit, in the early morning hours before Jackson's death, Murray withheld propofol and tried numerous drugs starting with valium at 1:30 a.m. Still not asleep by 10:40 a.m., Jackson demanded propofol and Murray complied. 20 minutes later is when Jackson was found not breathing.

Although Murray administered propofol, no evidence has surfaced proving he "purchased, ordered or obtained the medication under his medical license or Drug Enforcement Administration tracking number," said the Times. Murray said he wasn't the only doctor that had given Jackson the drug. Involuntary manslaughter charges could be the end result for him as the investigation continues.

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Here's an interesting article on Propofol...

http://hubpages.com/hub/Propofol-Diprivan--what-is-it

I get the idea from the article that Propofol is a pretty dangerous drug. There is a very fine line between anesthetized and overdosed.

From what I've been reading there will be a lot of questions (and should be) about how this drug was procured and why it was used in a home setting in the first place. According to drug.com and webMD.com. According to the "warnings and precautions" on the webMD.com site

    "Use of DIPRIVAN Injectable Emulsion infusions for both adult and pediatric ICU sedation has been associated with a constellation of metabolic derangements and organ system failures, referred to as Propofol Infusion Syndrome, that have resulted in death. The syndrome is characterized by severe metabolic acidosis, hyperkalemia, lipemia, rhabdomyolysis, hepatomegaly, cardiac and renal failure. The syndrome is most often associated with prolonged, high-dose infusions ( > 5 mg/kg/h for > 48h) but has also been reported following large-dose, short-term infusions during surgical anesthesia. In the setting of prolonged need for sedation, increasing propofol dose requirements to maintain a constant level of sedation, or onset of metabolic acidosis during administration of a propofol infusion, consideration should be given to using alternative means of sedation."

That anyone would be using this (typical surgical ward) drug in the home is almost beyond comprehension.

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